Some of the notable Wildlife species to look out for in the Karuma Wildlife Reserve include the Cape Buffaloes, the Elephants, the Uganda Kobs, the Rothschild’s giraffes, the vervet monkeys, the Olive baboons, the Black and white Colobus monkeys, L’Hoest’s monkeys, the Topis, the Hippos, the Oribis, occasionally the Lions and the Leopards among others.

Besides the Wildlife and bird species within the Wildlife Reserve, it is widely known for the roaring Karuma falls on the Victoria Nile and is perfect for sigh seeing. This waterfalls is not very far from the powerful Murchison Falls, hence can enjoy two of the greatest waterfalls in Uganda while on a safari.